STUDIES ON MORPHINE DISPOSITION: INFLUENCE OF RENAL FAILURE ON THE KINETICS OF MORPHINE AND ITS METABOLITES
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چکیده
منابع مشابه
Studies on morphine disposition: influence of renal failure on the kinetics of morphine and its metabolites.
The influence of renal failure on the disposition of morphine and its metabolites was studied in nine patients with end-stage renal failure undergoing transplantation, and compared with five healthy anaesthetized patients. All patients received morphine sulphate pentahydrate 10 mg i.v. over 30 s, as part of a balanced anaesthetic technique. Venous blood samples were collected for up to 24 h, an...
متن کاملStudies on morphine disposition: influence of general anaesthesia on plasma concentrations of morphine and its metabolites.
The kinetics of morphine were studied during balanced anaesthesia in 10 patients undergoing lower abdominal or body surface surgery, and compared with those obtained in nine awake patients receiving morphine i.v. for the relief of chronic non-cancer pain. All patients received morphine sulfphate pentahydrate 10 mg i.v. over 30 s. Venous blood samples were collected for up to 180 min, and plasma...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1989
ISSN: 0007-0912
DOI: 10.1093/bja/62.1.28